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Jian-Ting Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation
and inhibits antigen-induced mediator release from human lung fragments in a concentration-related fashion
Overexpression of CaMKIIγ or AKT abolishes the effects of SKF-96365 on cancer cells
Molecular Weight: 278
GZD824 dimesylate - CAS# 1421783-64-3 Catalog No.:M16476-C Jian-Ting Synthesis and Identification ofGZD824 dimesylate (HQP1351 dimesylate) is a potent and orally active pan Bcr Abl inhibitor. GZD824 dimesylate potently inhibits a broad spectrum of Bcr Abl mutants. GZD824 dimesylate strongly inhibits native Bcr Abl and Bcr AblT315I with IC50s of 0. 34 nM and 0. 68 nM, respectively. GZD824 dimesylate has antitumor activity. Product information CAS Number: 1421783 64 3 Molecular Weight: 724. 77 Formula: C31H35F3N6O7S2 Chemical Name: 4 methyl N {4 [(4
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